Testicular, Penile, and Rare Malignancies

First-Line PD-1 Blockade, Cisplatin, Paclitaxel Effective for Advanced PSCC in Retrospective Study
Penile squamous cell carcinoma (PSCC) is a rare disease with a poor prognosis. There is a lack of data on first-line (1L) regimens for distant metastatic PSCC, with a 2-year overall survival (OS) rate of just 21%. As the preferred strategy of combined chemotherapy lacks substantial progression-free survival (PFS) and OS rates, the use of immune checkpoint blockades (ICBs) in conjunction with chemotherapy has been studied for the disease, providing better results for patients. However, this combination has been studied sparingly. ...
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