Little data exist on the effects of performance status (PS) on the oncological outcomes of patients with prostate cancer (PCa). To determine the efficacy of systemic therapies in patients with worse PS who are treated for high-risk nonmetastatic prostate cancer, metastatic hormone-sensitive prostate cancer (mHSPC), and metastatic/nonmetastatic castration-resistant prostate cancer (nmCRPC), a team of researchers performed a meta-analysis to study several randomized, controlled trials (RCTs) to determine a correlation. ...
nmCRPC
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A clinical trial sought to determine if flutamide is more effective with or without PROSTVAC in patients with nmCRPC.
Updated AUA/SUO Guideline on Advanced Prostate Cancer Offers New Recommendations on Imaging, Testing
The updated guideline emphasizes the use of PSMA PET for periodic staging, as well as the use of ADT.
Dr. Sternberg shares the therapeutic options for nmCRPC patients, how stage at diagnosis impacts these options, and more.
Researchers conducted a study to determine PSA response and MFS in patients with nmCRPC treated with APA.
Existing literature on adverse events in ARSi drugs was examined to determine how the drugs’ side-effect profiles compare.
The first report on preoperative NLR in predicting nodal involvement for patients with non-metastatic prostate cancer.
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Curated clinical content on prostate cancer types, therapies, and technologies
Conference Coverage
Dr. Galsky shares the first OS data update on the CheckMate 274 trial, which he gave at the 2024 EAU Congress.
Dr. Julian Chavarriaga describes his study on using miRNA as a liquid biomarker to detect malignancy in testicular masses.
Dr. Finati discusses what the future has in store for further investigation utilizing larger patient databases.
Drs. Grasso and Verhovsky discuss the potential of endoscopic treatment with surveillance for patients with bladder cancer.
Dr. Myers and colleagues challenge the current paradigm of discouraging additional BCG therapy for "unresponsive" NMIBC.
Dr. Canfield shares real-world active surveillance among men with localized PC tested with the genomic prostate score assay.
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Metabolites were shown to have “the highest potential for differences between urine levels in healthy and BC patients."
Smoking increased risk of urothelial carcinoma “more than expected” in patients with certain genetic risk factors.
Researchers developed a model to predict bladder cancer recurrence by combining microRNA with a pathological factor.
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