Magnetic resonance imaging (MRI) is a common tool for the staging of prostate cancer (PCa), but prior research has shown it has poor sensitivity despite a high specificity rate. As prostate-specific membrane antigen (PSMA) is overexpressed in PCa, the use of PSMA positron emission tomography/computed tomography (PET/CT) can provide a superior alternative to MRI, but research on the use of second-generation PSMA PET radioligands is limited. ...
Prostate Cancer Diagnostics
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The FDA has accepted an NDA for TLX007-CDx, a cold kit for the preparation of PSMA-PET imaging for prostate cancer.
About 1 in 12 patients who undergo non-targeted prostate biopsy with a result of GGG 1 PC may have more aggressive cancer.
Patients were sorted into groups based on modifiable lifestyle behaviors and genetic risk.
Researchers trained and externally validated an AI system to detect Gleason grade group 2 or higher cancers.
Dr. Calais provides his list of the clinical trials of interest on imaging, RLT, and prostate cancer from the SNMMI meeting.
Dr. Calais shares his thoughts on the sessions or abstracts that are of the most importance for practicing GU oncologists.
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Conference Coverage
Vishnu Murthy discusses the real-world efficacy and toxicity of 177Lu-PSMA-617 for mCRPC.
Rana McKay, MD, provides commentary on the safety of 89Zr-girentuximab PET/CT for treating clear cell renal cell carcinoma.
Dr. Calais provides his list of the clinical trials of interest on imaging, RLT, and prostate cancer from the SNMMI meeting.
Dr. Calais shares his thoughts on the sessions or abstracts that are of the most importance for practicing GU oncologists.
Dr. Sartor discusses the PSMAfore study, which examined [177Lu]Lu-PSMA-617 radioligand therapy in taxane-naive mCRPC.
Dr. Johnson provides an overview of the SECuRE study, a phase 1/2a theranostic trial for treatment of PSMA-expressing mCRPC.