Data from a recent multicenter study revealed that although the majority of clinical trials exploring adjuvant therapy for the treatment of renal cell carcinoma (RCC) concentrate on clear cell (ccRCC), patients with high-risk non-clear cell RCC (nccRCC) exhibit comparable 5-year cancer-specific and overall survival outcomes. These findings highlight that patients with nccRCC may benefit from adjuvant therapy, potentially enhancing long-term survival rates. ...