A new study on the prognostic value of perinephric fat, renal sinus fat, and renal vein invasion in patients with pT3a RCC. Researchers analyzed the data from patients who received anti–LAG-3 and anti–PD-1. While RLRN and TLRN procedures were found to have similar efficacy, TLRN also resulted in better surgical specimen integrity. Dr. Saby George continues with the survival implications and ramifications from the CheckMate 214 long-term data. Dr. Saby George provides details on CheckMate 67T for the utility of subcutaneous nivolumab for advanced or metastatic ccRCC. Dr. Powles gives his unique feedback on what to make of KEYNOTE-564 and how aRCC frontline options should be compared. The panel shared their excitement for the road ahead in kidney cancer. The panel addressed different dosing scenarios and shared tips on how to counsel patients on their treatment. The panel shared their thoughts on quality of life data presented from the LITESPARK-005 trial of belzutifan. The panel discussed the impact of a subcutaneous formulation of nivolumab. The panel discussed the role of SBRT and some exciting studies like SAMURAI. The panel discussed CheckMate 9ER, which assessed quality of life outcomes in patients receiving cabozantinib/nivolumab. The panel shared their thoughts on the 8-year follow-up data from CheckMate 214. The panel discussed two studies that assessed adjuvant treatment: KEYNOTE-564 and CheckMate 914. The quality of patient-reported outcome analyses over the past 15 years is unknown, as reporting has waned. The panel forecasted some of the major questions that will be answered regarding belzutifan, triplet combinations, and more. The panel transitioned to relevant considerations from the CheckMate 67T study and thoughts on subcutaneous nivolumab. The panel highlighted the CheckMate 9ER study and implications for clinical practice. The panel swapped opinions on data pertaining to CheckMate 914, CheckMate 214, and IMDC selection criteria. The panel discussed the groundbreaking OS results from the KEYNOTE-564 study and implications for their practice.