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mHSPC
Metastatic hormone-sensitive prostate cancer
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Comparing Alpha and Beta Emitters, and Looking to the Future of Advanced Prostate Cancer Care
David Morris, MD, FACS
mHSPC
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December 12, 2024
The panel explores the distinct roles of alpha and beta emitters in radiopharmaceutical therapy for prostate cancer care.
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Upcoming Trials for mHSPC and mCRPC and Next-Generation Sequencing
David Morris, MD, FACS
mHSPC
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December 12, 2024
The expert panel discusses emerging biomarkers and treatment combinations for CRPC and mHSPC.
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The Growing Field of Radioligand Therapy and Radium Use for mHSPC and mCRPC
David Morris, MD, FACS
mHSPC
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December 12, 2024
The evolving role of RLT and radium-223 in managing metastatic mHSPC and CRPC is discussed.
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Treatment Considerations After New Data: ARASENS, ARANOTE, and PEACE-3
David Morris, MD, FACS
CRPC
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December 12, 2024
The panel examines the impact of the latest data from ARANOTE and PEACE-3 in part three of this roundtable.
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Patient Characteristics to Consider for Doublet, Triplet Therapy in mHSPC and mCRPC
David Morris, MD, FACS
mHSPC
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December 12, 2024
The panelists discuss key considerations for patient selection in doublet and triplet therapies for mHSPC and CRPC.
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Biomarkers and Imaging in Upfront Metastatic Prostate Cancer Diagnosis
David Morris, MD, FACS
Roundtable
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December 12, 2024
In part one of this roundtable, the panel discusses advances in imaging and tailored treatment strategies for prostate cancer
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RAVENS: Analyzing Radium-223 vs SABR for Oligometastatic HSPC
Ana Kiess, MD, PhD
mHSPC
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November 21, 2024
Ana Kiess, MD, PhD, of Johns Hopkins Medicine, reviews the phase II RAVENS trial on radium-223 with SABR versus SABR alone.
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Docetaxel Plus 177Lu Boosts Antitumor Activity in mHSPC Over Docetaxel Alone
Emily Menendez
mHSPC
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November 19, 2024
The phase II UpFrontPSMA study evaluated the use of [177Lu]Lu-PSMA-617 administered before docetaxel.
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Apalutamide vs Enzalutamide: Insights on Real-World Survival Benefits and Clinical Implications
Marc Greenstein, DO
mCSPC
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October 31, 2024
Dr. Greenstein shares insights on the overall survival benefit of apalutamide over enzalutamide in a recent real-world study.
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Assessing the ARANOTE Trial: Role of Darolutamide in Enhancing ADT for HSPC
Andrew Laccetti, MD, MS
nmHSPC
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September 25, 2024
At ESMO 2024, experts discuss androgen-deprivation therapy in HSPC as well as the ARANOTE trial.
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Transformations in mPC: Risk Stratification, Therapy Approaches for Hormone-Sensitive Disease
Andrew Laccetti, MD, MS
mHSPC
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September 25, 2024
Experts discuss mHSPC discuss risk stratification, developed novel approaches for treatment, and treatment sequencing.
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Using rPFS, cPFS as Surrogate Primary End Points May Expedite mHSPC Trials
Emily Menendez
mHSPC
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February 28, 2024
Phase III mHSPC trials can take up to a decade to complete when OS is used as the primary endpoint.
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Low PNI May Indicate Poor Treatment Response in Patients With mHSPC Undergoing ADT
Emily Menendez
mCSPC
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October 12, 2023
The PNI is commonly used as a prognostic factor for malignant tumors, but its potential use for prostate cancer is unknown.
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mHSPC With Suboptimal PSA Response Linked to Poor Survival Outcomes
Emily Menendez
mCSPC
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October 12, 2023
Patients with a suboptimal PSA response who are administered intensified ADT often experience worse survival outcomes.
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How Does Performance Status Affect the Efficacy of Systemic Therapy for Prostate Cancer?
Emily Menendez
Prostate Cancer
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October 12, 2023
A meta-analysis sought to determine the efficacy of systemic therapies in patients with PCa and poor performance status.
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Updated AUA/SUO Guideline on Advanced Prostate Cancer Offers New Recommendations on Imaging, Testing
Emily Menendez
Prostate Cancer
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October 12, 2023
The updated guideline emphasizes the use of PSMA PET for periodic staging, as well as the use of ADT.
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CHAARTED Trial Post Hoc Analysis Reveals QOL and Survival Outcomes
Emily Menendez
ASCO 2023
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October 12, 2023
Results from the CHAARTED trial demonstrated that ADT and docetaxel improves OS and QOL at 12 months compared with ADT alone.
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Use of ARATs as First-line mHSPC Treatment Grows, NLR and PSA Serve as Prognostic Factors
Emily Menendez
mCSPC
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October 12, 2023
Researchers studied several trials including LATITUDE and STAMPEDE to find similar characteristics among ARAT treatments.
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Incidence of Clinical Fracture in mHSPC: Zoledronic Acid, Docetaxel, or Both?
Emily Menendez
AUA 2023
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October 12, 2023
The STAMPEDE trial examined the addition of zoledronic acid, docetaxel, or both to ADT for the treatment of mHSPC.
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Radiation’s Role in Metastatic Prostate Cancer Growing, Evolving
Leah Lawrence
Prostate Cancer
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October 12, 2023
Several physicians highlight the newest data on radiation for metastatic prostate cancer and its role moving forward.
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