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ESMO 2022
European Society for Medical Oncology Congress 2022
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Overall Survival Results of STAMPEDE Protocol Phase 3 Trials
Akhil Abraham Saji, MD
Journal
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October 12, 2023
Abiraterone acetate + prednisolone is compared to enzalutamide + AAP for mHSPC cancer starting androgen-deprivation therapy.
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Updated Results From the Phase 3 PROpel Trial
Akhil Abraham Saji, MD
Journal
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November 11, 2022
Results from the phase 3 PROpel trial on abiraterone + olaparib vs abiraterone + placebo as first-line therapy for MCRPC
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Neoadjuvant Platinum-Based Chemotherapy Effective for Metastatic Penile SCC
Leah Lawrence
ESMO 2022
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November 11, 2022
Neoadjuvant platinum-based chemotherapy has been found effective for treating metastatic penile squamous cell carcinoma.
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Neurodevelopmental Disorders Associated With Risk for Testicular Seminoma
Leah Lawrence
ESMO 2022
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November 11, 2022
A new study has found an association between neurodevelopmental disorders and testicular seminoma.
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CLEAR: Lenvatinib, Pembrolizumab Showed Continued Benefit in Advanced RCC
Leah Lawrence
ESMO 2022
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March 10, 2023
CLEAR study results showed that treatment with first-line lenvatinib plus pembrolizumab had clinical benefit at 2 years.
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Neoadjuvant Radio-Immunotherapy Safe Option for Locally Advanced Bladder Cancer
Leah Lawrence
ESMO 2022
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October 21, 2022
The RACE IT trial finds neoadjuvant radio-immunotherapy followed by radical cystectomy a safe and feasible treatment option.
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Androgen Receptor Gene Alterations and mCRPC Treatment Outcomes
Patrick Daly
ESMO 2022
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November 11, 2022
Patients with mCRPC with AR alterations had significantly worse survival outcomes compared with patients with wild-type.
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Network Meta-Analysis of mCSPC Treatment Options
Patrick Daly
ESMO 2022
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August 23, 2023
A meta-analysis found that triplet regimens with darolutamide and APP improved survival in mCSPC with high volume of disease.
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KEYNOTE-365: Pembrolizumab With AAP in mCRPC
Patrick Daly
ESMO 2022
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November 11, 2022
Pembro plus AAP sustained antitumor activity with acceptable safety signals in patients with mCRPC after 2 years.
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ADT Plus APA With or Without AAP in High-Risk Prostate Cancer
Patrick Daly
ESMO 2022
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November 11, 2022
PRESTO trial results show adding APA and AAP to ADT improved biochemical PFS in patients with relapsed prostate cancer.
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ESMO 2022: Enfortumab Vedotin Plus Pembrolizumab Versus Pembrolizumab Alone for Urothelial Carcinoma
The Uromigos
The Uromigos
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November 11, 2022
Peter O'Donnell describes the randomized phase 2 study on enfortumab vedotin and pembrolizumab against pembrolizumab alone.
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177Lu-PSMA Radioligand Therapy in Very Old Patients With mCRPC
Patrick Daly
ESMO 2022
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November 11, 2022
177Lu-PSMA-RLT showed efficacy and safety consistent with published evidence in cohort of very old patients with mCRPC.
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Assessing ODM-208 in Patients With mCRPC: The CYPIDES Trial
Patrick Daly
ESMO 2022
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November 11, 2022
Karim Fizazi discussed preliminary findings on ODM-208, a first-in-class CYP11A1 inhibitor at ESMO 2022.
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Abiraterone Acetate, Prednisolone, and Enzalutamide With ADT in mHSPC
Patrick Daly
ESMO 2022
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October 12, 2023
Late-breaking data from 2 randomized phase 3 trials that followed STAMPEDE protocol were presented at the ESMO Congress 2022.
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ESMO 2022: Breaking Down the Phase 3 PIVOT-09 Study
The Uromigos
The Uromigos
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November 11, 2022
Nizar Tannir describes this randomized phase 3 study on bempegaldesleukin plus nivolumab as presented at ESMO.
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ESMO 2022: PRESTO - A Phase 3 Androgen Annihilation in Biochemically Relapsed Prostate Cancer
The Uromigos
The Uromigos
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November 11, 2022
The phase III PRESTO study examined the effects of androgen suppressants on biochemically relapsed prostate cancer.
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ESMO 2022: Summary of ESMO Adjuvant RCC Trials
The Uromigos
The Uromigos
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November 11, 2022
Axel Bex summarizes the ipi/nivo, pembro and atezo studies that were presented at ESMO 2022.
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ESMO 2022: PROSPER Study of Neoadjuvant Nivolumab in RCC
The Uromigos
The Uromigos
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August 1, 2023
Mohamad Allaf gives a recap of the open-label PROSPER study on neoadjuvant nivolumab in RCC.
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Enzalutamide Plus Androgen Deprivation Therapy in mCRPC
Patrick Daly
ESMO 2022
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March 3, 2023
Researchers evaluated immune effects of enzalutamide in patients with metastatic castration-resistant prostate cancer on ADT.
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Pembrolizumab and Olaparib Versus Next-Generation Hormonal Agents in mCRPC
Patrick Daly
ESMO 2022
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November 11, 2022
Pembrolizumab plus olaparib did not improve survival versus alternating from abiraterone or enzalutamide in mCRPC.
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