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Non-Muscle Invasive Urothelial Carcinoma
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Natural Language Processing Model Identifies High-Risk NMIBC With Good Performance
Emily Menendez
Non-Muscle Invasive Urothelial Carcinoma
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November 10, 2023
Researchers sought to develop an NLP model to describe patients and tumor characteristics to more easily aggregate data.
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ATLAS: Analyzing UGN-102, TURBT for Intermediate-Risk NMIBC
David Ambinder, MD
Non-Muscle Invasive Urothelial Carcinoma
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October 30, 2023
Is there a better way to manage low-grade NMIBC? Adding UGN-102 to the current standard of care may be the answer.
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SunRISe-1: TAR-200 in BCG-Unresponsive High-Risk NMIBC
Zachary Bessette
ESMO 2023
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October 27, 2023
Results of the phase 2b SunRISe-1 trial showed TAR-200 yields complete responses in BCG-unresponsive high-risk NMIBC.
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Novel Erdafitinib Delivery System Safe, Well-Tolerated for NMIBC
Emily Menendez
ESMO 2023
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October 24, 2023
The TAR-210 delivery system provides a continuous release of erdafitinib to the bladder while limiting systemic toxicities.
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THOR-2 Cohort 1: Recurrence-Free Survival in FGFR-Altered NMIBC After Erdafitinib, Prior BCG
Zachary Bessette
ESMO 2023
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October 23, 2023
An LBA shed light on the effects of erdafitinib in patients with high-risk NMIBC with select FGFR alterations after BCG.
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Previewing ESMO 2023: The Latest Genitourinary Research, Trials Due to Be Presented
Akhil Abraham Saji, MD
RLT
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October 5, 2023
This review highlights some of the most exciting abstracts and presentations in GU oncology at the ESMO Congress 2023.
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SWOG S1605 Yields “Modest” Efficacy for Atezolizumab in BCG-Unresponsive High-Risk NMIBC
Peter C. Black, MD
Non-Muscle Invasive Urothelial Carcinoma
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September 29, 2023
Dr. Black shares the basis for testing atezolizumab in BCG-unresponsive NMIBC as well as the implications of SWOG S1605.
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How Does Sasanlimab Fare in High-Risk, BCG-Naïve NMIBC?
Raj Satkunasivam, MD, MS, FRCSC
Non-Muscle Invasive Urothelial Carcinoma
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September 8, 2023
Dr. Satkunasivam shares the inspiration for combining sasanlimab with BCG in patients with high-risk, BCG-naïve NMIBC.
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Dr. Sandip Prasad on ATLAS and ENVISION for Intermediate-Risk, Low-Grade NMIBC
Sandip Prasad, MD, MPhil
Non-Muscle Invasive Urothelial Carcinoma
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August 30, 2023
Dr. Prasad provides overviews of ATLAS and ENVISION and opines on whether UGN-102 is a practice-ready alternative to TURBT.
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Exploring NMIBC Options in the Face of BCG Shortages, Failure
Leah Lawrence
Non-Muscle Invasive Urothelial Carcinoma
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August 17, 2023
Several urologists weigh in on BCG, its role in NMIBC treatment, shortages, and strategies to treat BCG-unresponsive disease.
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UGN-102 May Be Superior to TURBT for Managing Low-Grade, Intermediate-Risk NMIBC
Zachary Bessette
Non-Muscle Invasive Urothelial Carcinoma
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August 8, 2023
The ATLAS study demonstrated the superiority of UGN-102 over TURBT for patients with low-grade, intermediate-risk NMIBC.
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ATLAS, ENVISION Trials Demonstrate Benefit of UGN-102 for NMIBC
Emily Menendez
Non-Muscle Invasive Urothelial Carcinoma
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August 4, 2023
UGN-102 is a sustained-release, hydrogel-based formula that allows bladder tissue to be exposed to mitomycin longer.
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Predicting Differing Responses to Intravesical BCG Therapy for NMIBC
Emily Menendez
Non-Muscle Invasive Urothelial Carcinoma
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July 10, 2023
Through molecular profiling, three different BCG response subtypes were found: BRS1, BRS2, and BRS3.
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RESECT Study Results and Variations in NMIBC Recurrence Between Sites
Emily Menendez
ASCO 2023
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June 1, 2023
An observational study sought to determine variation in recurrence after TURBT between sites taking part in the RESECT study.
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FDA Approval of Adstiladrin Expands Options for Patients With BCG-Unresponsive NMIBC
Akhil Abraham Saji, MD
Non-Muscle Invasive Urothelial Carcinoma
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May 30, 2023
FDA approval of Adstiladrin for use in BCG-unresponsive NMIBC expands the armamentarium for treatment of high-risk NMIBC.
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Understanding the Financial Considerations and Treatment Costs Related to NMIBC
Akhil Abraham Saji, MD
Non-Muscle Invasive Urothelial Carcinoma
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May 1, 2023
NMIBC-associated costs vary widely across types of treatments utilized, health systems, and regions of the country.
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Global Variation in Early Recurrence After TURBT in the RESECT Study
Zachary Bessette
AUA 2023: Focus on Bladder Cancer
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April 29, 2023
There is significant inter-site variation in recurrence of NMIBC after TRUBT in the RESECT study, according to new research.
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Tolerability and Efficacy of BCG After NMIBC Recurrence Following Bladder-Preserving Therapy
Emily Menendez
AUA 2023: Focus on Bladder Cancer
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April 28, 2023
Study results indicate an alternative strategy to radical cystectomy for comprehensive bladder-preserving therapy for MIBC.
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Analyzing a New Treatment for Patients With NMIBC Who Failed BCG Therapy
Emily Menendez
Non-Muscle Invasive Urothelial Carcinoma
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April 28, 2023
No nonsurgical treatments currently exist for patients with NMIBC who did not respond to BCG therapy.
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Risk-Based Substratification Improves Surveillance Costs for Patients With HR-NMIBC
Emily Menendez
AUA 2023: Focus on Bladder Cancer
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April 28, 2023
Patients with high-risk NMIBC who underwent TURBT from November 1993 to April 2019 were retrospectively evaluated.
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