Dr. David McDermott joins the podcast to review the top data from 2024 in the renal cell carcinoma field. Dr. Jim Brugarolas joins the podcast to discuss his talk from IKCS 2024 and the broad topic of resistance to HIF inhibitors. Dr. Andrew Smith, chair of diagnostic imaging at St. Jude's, joins the podcast to discuss the emerging field of radiomics. Listen to the podcast format of the kidney cancer panel on IO after IO therapy from Uromigos Live 2024. Listen to the podcast format of the kidney cancer panel on TKI vs Ipi/Nivo vs IO/TKI from Uromigos Live 2024. Tom and Brian finish discussing bladder and kidney cancer highlights from ESMO 2024. Lothar Bergmann describes this investigator-initiated trial of Ipi/Nivo vs SOC in Non-clear Cell RCC. Brad McGregor joins Brian and Tom to discuss a new HIF inhibitor, NKT2152, and preliminary data in RCC. Drs. Cristina Suárez, Elena Castro, and María Teresa Bourlon discuss recent ESMO guideline changes on GU cancers. Naomi Haas joins Tom and Brian in New York City at the World GU Conference to discuss several RCC topics. Dr. Eric Jonasch discusses the process of guideline modification and updates in adjuvant, front-line and refractory RCC. Dr. David Braun discusses his organization of immune therapies into four groups and describes novel treatments and targets. Drs. Cristina Suárez, Elena Castro, and María Teresa Bourlon host the first Spanish-language ASCO episode for The Uromigos. Drs. Axel Bex, Christian Blank, Laura Mertens and Micheil Van der Heijden get a chance to win The Uromigos Cup. Drs. Viktor Grünwald, Boris Hadaschik and Gunhild Von Amsberg answer trivia for the Uromigos Cup qualifying round. Drs. Nobuaki Matsubara, Hiroshi Kitamura and Yuji Miura answer trivia questions set by Tom and Brian for the Uromigos Cup. Drs. Danny Heng, Christian Kollmannsberger and Kala Sridhar attempt to take on Team LA to win the Uromigos Cup. Silke Gillessen joins Brian and Tom to give a preview of this year's ASCO annual meeting. The Uromigos discuss adjuvant therapy in kidney and bladder cancer trials including KEYNOTE-564. Dr. McDermott discusses the similarities between current melanoma trials and kidney cancer treatments.