Dr. Jonathan Rosenberg discusses the treatment-related side effects of EV/pembro for bladder cancer. Drs. Cristina Suárez, Elena Castro, and María Teresa Bourlon host the first Spanish-language ASCO episode for The Uromigos. Drs. Axel Bex, Christian Blank, Laura Mertens and Micheil Van der Heijden get a chance to win The Uromigos Cup. Drs. Viktor Grünwald, Boris Hadaschik and Gunhild Von Amsberg answer trivia for the Uromigos Cup qualifying round. Dr. Aditya Bagrodia discusses new drugs and studies for NMIBC that were presented at this year's AUA meeting. Drs. Nobuaki Matsubara, Hiroshi Kitamura and Yuji Miura answer trivia questions set by Tom and Brian for the Uromigos Cup. Drs. Danny Heng, Christian Kollmannsberger and Kala Sridhar attempt to take on Team LA to win the Uromigos Cup. Silke Gillessen joins Brian and Tom to give a preview of this year's ASCO annual meeting. Tom and Brian are joined by David Penson to discuss upcoming presentations to look forward to at AUA. Alison Birtle gives an update on the POUT trial on the use of adjuvant chemotherapy after nephroureterectomy for UTUC. Dr. Galsky describes the OS signal data from CheckMate-274 on adjuvant nivolumab for muscle-invasive bladder cancer. Dr. Matt Galsky, Brian, and Tom discuss the IMvigor011 trial data that was presented at EAU 2024. Michiel Van der Heijdan explores the role of radiotherapy and other neoadjuvant combinations for MIBC. Dr. Galsky discusses his phase 2 study evaluating the effects of gem/cis/nivo followed by nivolumab in responders. The Uromigos discuss adjuvant therapy in kidney and bladder cancer trials including KEYNOTE-564. Andrea Apolo, MD, discusses the phase III AMBASSADOR study that investigated adjuvant pembrolizumab against observation. Elena Castro, Begoña Valerrama and Cristina Suárez analyze some of the urothelial carcinoma research highlights of 2023. Dr. Kala Sridhar joins the podcast to discuss updates and advancements in the bladder cancer field in 2023. Matt Galsky continues his discussion on ctDNA in bladder cancer and covers topics such as candidate versus panel approaches. Dr. James Catto joins the podcast to compare robotic cystectomy against open cystectomy for patients with bladder cancer.