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Upper Tract Urothelial Carcinoma
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Blood-Based Liquid Biopsy for Patients With UTUC
Hooman Djaladat, MD
Upper Tract Urothelial Carcinoma
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March 28, 2024
Dr. Djaladat discusses how the presence of specific biomarkers, such as CK|V oncosomes and D|CK|V cells, correlate with RFS.
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Carboplatin Versus Cisplatin in UTUC
Alison Jane Birtle, MD, MBBS, MRCP, FRCR
Upper Tract Urothelial Carcinoma
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March 15, 2024
Dr. Birtle describes the utility of carboplatin versus cisplatin in this regimen and discusses metastasis-free survival.
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Potential OS Benefit of Adjuvant Chemotherapy for UTUC
Alison Jane Birtle, MD, MBBS, MRCP, FRCR
Upper Tract Urothelial Carcinoma
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March 21, 2024
Dr. Birtle highlights the trial's findings regarding the long-term overall survival benefit of adjuvant chemotherapy.
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POUT: Adjuvant Chemotherapy After Nephroureterectomy for Patients With UTUC
Alison Jane Birtle, MD, MBBS, MRCP, FRCR
Upper Tract Urothelial Carcinoma
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March 15, 2024
The POUT trial investigated adjuvant chemo for improving disease-specific survival in patients with UTUC.
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Blood-Based Liquid Biopsies Detect CTCs, Oncosomes in Patients With UTUC
Emily Menendez
Upper Tract Urothelial Carcinoma
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March 11, 2024
Liquid biopsy can benefit patients with UTUC by detecting rare events at higher incidences compared to tissue-based samples.
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Adjuvant Chemotherapy May Improve Overall Survival in UTUC
Katy Marshall
Upper Tract Urothelial Carcinoma
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March 1, 2024
Patients in the POUT trial were randomized to either a platinum-based adjuvant chemotherapy arm or a surveillance arm.
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Prognostic Capabilities of Variant Histology for Patients With UTUC
Katy Marshall
Upper Tract Urothelial Carcinoma
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March 11, 2024
Researchers investigated the ability of variant histology to predict oncological outcomes.
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Hem-o-lok System Prevents Spread of Tumor Cells in Radical Nephroureterectomy for UTUC
Emily Menendez
Upper Tract Urothelial Carcinoma
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December 20, 2023
The system provides a seal of the upper urinary tract to prevent urine leakage and can prevent the spread of tumor cells.
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Five-Item Frailty Index Can Increase Prognosis, Decision-Making in Patients With UTUC After RNU
Emily Menendez
Upper Tract Urothelial Carcinoma
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December 12, 2023
Use of an sFI may increase accuracy in predicting complications and prognosis, as well as improve decision-making.
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Defining the Biology of Upper Tract Urothelial Carcinoma and Therapy Implications
Christopher Wallis, MD, PhD, FRCSC
Upper Tract Urothelial Carcinoma
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March 11, 2024
Drs. Faltas and Wallis delve into the genomics of UTUC, including the evolution of disease and FGFR inhibition potential.
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Nephron-Sparing and Chemoablation in Upper Tract Urothelial Carcinoma
Christopher Wallis, MD, PhD, FRCSC
Upper Tract Urothelial Carcinoma
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December 18, 2023
Drs. Murray and Wallis discuss optimal patient selection, size criteria, and surgical ablation and chemoablation together.
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Nomogram Finds Suitable Candidates for Endoscopic Management of LG-NMI UTUC
Emily Menendez
Upper Tract Urothelial Carcinoma
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December 12, 2023
The nomogram outperformed 2 conventional models in predictive accuracy and showed higher benefit in decision curve analysis.
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Novel Use of ctDNA to Identify Muscle-Invasive, Non–Organ-Confined UTUC
Roger Li, MD
Upper Tract Urothelial Carcinoma
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March 11, 2024
Dr. Li details what his study results suggested about ctDNA’s prognostic implications for survival in patients with UTUC.
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Ureteroscopic Surgery for Patients With UTUC
Katy Marshall
Upper Tract Urothelial Carcinoma
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November 14, 2023
The study compared ureteroscopic surgery with radical nephroureterectomy.
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Detection of ctDNA May Be an Effective Predictor for Muscle-Invasive, Non–Organ-Confined UTUC
Katy Marshall
Upper Tract Urothelial Carcinoma
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March 11, 2024
Researchers used whole-genome sequencing and a 152-gene panel to study the DNA of patients with high-risk UTUC.
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IHC Screening, AMS II Identify Lynch Syndrome in Patients With UTUC
Katy Marshall
Upper Tract Urothelial Carcinoma
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March 11, 2024
Investigators performed IHC of 4 DNA mismatch repair gene-related proteins (MMRPs) on all UTUC specimens.
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Experts Surveyed on Ideal Laser Setting During Endoscopic UTUC Treatment
Emily Menendez
Upper Tract Urothelial Carcinoma
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October 13, 2023
In URS and RIRS, pulse shapes were significantly different, with Ho:YAG being used in long-pulse and TFL in short-pulse mode.
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Nomogram Predicts Probability of Extraurothelial Recurrence in UTUC After RNU
Emily Menendez
Upper Tract Urothelial Carcinoma
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September 22, 2023
The novel nomogram demonstrated perfect performance in discrimination ability and clinical net benefit.
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Patients Over 70 Who Undergo Radical Nephroureterectomy for UTUC May Have Worse Outcomes
Emily Menendez
Upper Tract Urothelial Carcinoma
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September 8, 2023
Older patients over 70 years of age need improved care and management of UTUC to improve their outcomes.
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Platinum, Gemcitabine Combination Improves OS, CSS in UTUC
Emily Menendez
Upper Tract Urothelial Carcinoma
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August 18, 2023
Patients who had initiated AC 90 days after RNU were examined to determine a relation between treatment efficacy and timing.
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