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Muscle Invasive Urothelial Carcinoma
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Reviewing the Role of PD-L1 in Patients With Urothelial Carcinoma
Katy Marshall
Muscle Invasive Urothelial Carcinoma
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July 25, 2024
Researchers evaluated the data of 50 specimens from patients who underwent TURBT and cystectomy for UC.
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Updated MIBC Treatment Guidelines From AUA, ASCO, SUO
Katy Marshall
Muscle Invasive Urothelial Carcinoma
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July 10, 2024
The new recommendations included changes to neoadjuvant and adjuvant chemotherapy and radical cystectomy.
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Durvalumab Shows Significant Survival Benefits for Muscle Invasive Bladder Cancer in Phase 3 NIAGARA Trial
Brandon Twyford
Muscle Invasive Urothelial Carcinoma
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June 25, 2024
Results from the NIAGARA trial show significant survival benefits with durvalumab for muscle invasive bladder cancer.
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Whole-Genome Mutational Analysis for ctDNA Detection Shows Potential for UC
Emily Menendez
Urothelial Carcinoma Diagnostics
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June 21, 2024
WGS-based ctDNA detection offered a median lead time of 131 days over radiographic imaging.
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Atezolizumab With EBRT for Bladder Preservation in MIBC
Ovidio Fernandez Calvo, MD
Muscle Invasive Urothelial Carcinoma
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June 13, 2024
Dr. Calvo offers insights on an interim analysis of the atezobladderpreserve phase 2 clinical trial in MIBC.
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SURE-01/02: Perioperative SG Alone, With Pembrolizumab for Patients With MIBC
Antonio Cigliola, MD
Muscle Invasive Urothelial Carcinoma
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June 6, 2024
Drs. Cigliola and Nizam discuss the implications of the reported SURE-01/02 study interim results.
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Analyzing Efficacy, Safety of Atezolizumab, Radiotherapy for Patients With MIBC
Katy Marshall
Muscle Invasive Urothelial Carcinoma
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June 3, 2024
Of the 26 patients with pathological assessment upon safety visit, all reached pCR, while none received cystectomy.
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SURE-01/02: Perioperative Sacituzumab Govitecan for Patients With MIBC
Zachary Bessette
Muscle Invasive Urothelial Carcinoma
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June 1, 2024
Neoadjuvant SG shows promising clinical activity in patients with MIBC and may help avoid radical cystectomy.
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Disitamab Vedotin Plus Toripalimab Is Beneficial, Well-Tolerated in HER2+ MIBC
Emily Menendez
Muscle Invasive Urothelial Carcinoma
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May 31, 2024
Disitamab vedotin, a novel anti-HER2 antibody-drug conjugate, was paired with toripalimab, an anti–PD-1 monoclonal ...
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Analyzing Temporal Trends, Cancer-Specific Survival in MIBC Treated With Trimodal Therapy
Katy Marshall
Muscle Invasive Urothelial Carcinoma
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May 23, 2024
For patients with organ-confined urothelial carcinoma of urinary bladder, trimodal therapy is recommended.
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Nab-Paclitaxel Plus Nivolumab Benefits MIBC Outcomes Post-Radical Cystectomy
Emily Menendez
Muscle Invasive Urothelial Carcinoma
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May 5, 2024
New findings from the Nure-Combo trial examined the use of ABX with nivolumab followed by RC and adjuvant nivolumab.
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Radiation Therapy to Recurrence Sites for Patients Post-Radical Cystectomy
Zachary Bessette
Muscle Invasive Urothelial Carcinoma
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May 3, 2024
RT to recurrence sites may not have an effect on oncologic outcomes in patients with MIBC after RC.
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MIBC Comprehensive Genomic Profiling in Patients Treated With Neoadjuvant Therapy Prior to Radical Cystectomy
Zachary Bessette
Muscle Invasive Urothelial Carcinoma
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May 3, 2024
Identifying tumor biomarkers associated with pCR to neoadjuvant pembro or NAC prior to cystectomy in patients with MIBC.
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CheckMate 274: OS Outcomes for Patients With MIBC
Matthew Galsky, MD
Muscle Invasive Urothelial Carcinoma
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May 20, 2024
Dr. Galsky shares the first OS data update on the CheckMate 274 trial, which he gave at the 2024 EAU Congress.
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IMvigor011: Positive Surveillance Data Demonstrate Benefits of Signatera
Katy Marshall
Muscle Invasive Urothelial Carcinoma
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April 8, 2024
Signatera quantifies cancer and the time of any recurrence events to assist in identifying treatment options.
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Potential Benefit of NAC Before Radiation Therapy for Patients With MIBC
Katy Marshall
Muscle Invasive Urothelial Carcinoma
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March 27, 2024
Researchers analyzed the effects of NAC on complete and overall response as well as cancer-specific survival after RT.
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Evaluating the Sensitivity of 68Ga-FAP-2286 PET Imaging for Patients With MIBC
Katy Marshall
Muscle Invasive Urothelial Carcinoma
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March 15, 2024
Patients received 68Ga-FAP-2286 PET, and investigators recorded the SUVmax of 68Ga-FAP-2286 PET-positive lesions.
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Neoadjuvant Pembrolizumab, Radical Cystectomy for Patients With MIBC
Katy Marshall
Muscle Invasive Urothelial Carcinoma
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March 1, 2024
Data from 458 patients who underwent RC between October 2005 and October 2020 and 146 in the PURE-01 trial was analyzed.
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CheckMate 274: Estimating the Underlying Cure Fraction for Patients With High-Risk MIUC
Daniel M. Geynisman, MD
ASCO GU Symposium 2024
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January 30, 2024
Dr. Geynisman highlights the CheckMate 274 study into long-term survival following treatment with adjuvant nivolumab.
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Neoadjuvant Atezolizumab for Patients with MIBC
Tanya Jindal
ASCO GU Symposium 2024
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February 1, 2024
Tanya Jindal discusses the safety and efficacy of neoadjuvant atezolizumab prior to radical cystectomy for MIBC.
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