Dr. Swami investigated the efficacy of cabozantinib in combination with immune checkpoint inhibitors for mccRCC. Dr. Vandekerkhove explains her research on genomic testing in prostate cancer. Dr. Zakharia continues his commentary on the BTCRC-GU16-043 study investigating guadecitabine and durvalumab in accRCC. Dr. Zakharia explains why guadecitabine plus durvalumab may be a good treatment approach in patients with advanced RCC. Dr. Afari elaborates on the factors he identified that contribute to renal function improvement post-partial nephrectomy. Helen Gao highlights her comparative outcomes analysis of RNU and kidney-sparing surgery in the treatment of high-grade UTUC. Drs. Braun and Beckermann stress the importance of adopting an integrative approach to biomarker-based research in RCC. Drs. Braun and Beckermann review JAVELIN Renal 101, focusing on the impact of avelumab and axitinib treatment on RCC. Drs. Braun and Beckermann discuss the evolving significance of sarcomatoid histology in guiding treatment decisions for RCC. Dr. Mollica continues her discussion on prognostic factors and clinical outcomes in PSCC. Dr. Mollica highlights her recent research investigating prognostic factors and clinical outcomes for patients with PSCC. Dr. Galsky shares the first OS data update on the CheckMate 274 trial, which he gave at the 2024 EAU Congress. Dr. Joshi contextualizes the THOR study within the treatment landscape for FGFR2/3-altered advanced urothelial carcinoma. Dr. Iagaru discusses the safety findings and clinical implications of his research. Dr. Ulaner highlights 2 new clinical trials for prostate cancer staging and treatment at Hoag: MIRROR and 177Lu-PNT2002. Drs. Atkins and Beckermann weigh the potential of targeting Tregs in RCC treatment, particularly in relation to PD-1 therapy. Drs. Atkins and Beckermann consider biomarkers for patient selection for LAG-3 inhibition and increasing cure rates in RCC. Drs. Atkins and Beckermann discuss LAG-3 as a novel checkpoint inhibitor combined with anti-PD-1 for kidney cancer.cC Drs. Grasso and Verhovsky discuss the potential of endoscopic treatment with surveillance for patients with bladder cancer. Dr. Myers and colleagues challenge the current paradigm of discouraging additional BCG therapy for "unresponsive" NMIBC.